THE ROLE OF EFFECTIVE COMMUNICATION IN THE MANAGEMENT AND RESOLUTION OF INDUSTRIAL CRISES
ANTI-HYPERLIPIDEMIC POTENTIAL OF VITEX DONIANAETHANOLEXTRACTS ON POLOXAMER 407 INDUCED HYPERLIPIDEMIC AND NORMAL RATS
December 2, 2017
THE ROLE OF EFFECTIVE COMMUNICATION IN THE MANAGEMENT AND RESOLUTION OF INDUSTRIAL CRISES
ASSESSMENT OF DIETARY PATTERN AND NUTRITIONAL STATUS OF PEOPLE LIVING WITH HIV/AIDS ATTENDING SOME VOLUNTARY AND COUNSELLING TEST (VCT) UNITS IN KADUNA METROPOLIS
December 2, 2017
Show all

ANTILIPIDEMIC EFFECT OF WATER (H20) EXTRACT OF DESMODIUM VELUTINUM LEAVES ON ALBINO WISTAR RATS

 3,000

Category:

Contact Us

    08165312322, 08119982823
    08165312322

RESEARCH INFORMATION

: ANTILIPIDEMIC EFFECT OF WATER (H20) EXTRACT OF DESMODIUM VELUTINUM LEAVES ON ALBINO WISTAR RATS
: Chapter 1 – 5
: 55 Pages
: #3, 000
: Ms Word format

This study,ANTILIPIDEMIC EFFECT OF WATER (H20) EXTRACT OF DESMODIUM VELUTINUM LEAVES ON ALBINO WISTAR RATS contains concise information that will serve as a framework or guide for your project work. The project study is well-researched for academic purposes and are usually provided in complete chapters with adequate References.

Keywords:ANTILIPIDEMIC EFFECT OF WATER (H20) EXTRACT OF DESMODIUM VELUTINUM LEAVES ON ALBINO WISTAR RATS


ju

RESEARCH BODY

ABSTRACT

This study evaluated the antilipidemic activity of water extracts from leaves of Desmodium velutinum on albino wistar rats. The phytochemical analysis of the leaf extract showed the presence of tannins, saponins, alkaloids, soluble carbohydrates, flavonoids, reducing sugar, steroids, cyanide and terpenoids. The animals were treated with known drugs (atorvastatin 2ml). There were significantly reductions in HDL 13.00 1.41 mg/dl LDL 1.20 0.14 mg/dl and triglyceride 39.00 0.14 mg/dl, compared with water extract of Desmodium velutinum (0.5ml). when administered was found to significantly reduce lipid plasma which was LDL 1.90 0.00mg/dl, triglyceride 50.00 0.00mg/dl and increase HDL 25.00 0.00 mg/dl which is the good cholesterol. The water extract of Desmodium velutinum leaf can possibly normalize the plasma lipid when compared with the group given atorvastatin. The phytochemicals analysis showed that the association between these complexes and compounds and other constituent play an important role in the biological activity of the leaf. This study suggested that the water extract of D.velutinum leaf posses hypolipidemic as well as antilipidemic effect.

CHAPTER ONE

INTRODUCTION

  • BACKGROUND OF STUDY

Lipid  and  lipoprotein  abnormalities  play  a  major  role  in  the

development and progression of coronary artery diseases. Low levels of high density lipoprotein cholesterols have been identified as independent coronary risk factors (Rodrigue et al., 2010). High level of blood cholesterol is responsible for circulatory system disorder. Increase level of low density lipoprotein (LDL) is alarming for cardiovascular diseases and their risk is increased many times (Harman et al., 2011).

In developing countries, the occurrence of heart diseases increases rapidly (Nordestgard et al., 2010). Medical studies show that about 70% of adults over 50 years old suffer atherosclerosis. (Sherien and Azza, 2009). A large number of synthetic hypolipidemic drugs are available in market. Long term use of these drugs cause serious side effects, and are costly.

A medicinal plant is any plant which in one or more of its organ, contains substance that can be used for therapeutic purpose or which is a precursor for synthesis of useful drugs (Sivakumar et al., 2007). Plant contains a large number of bioactive phytochemicals that are responsible for pharmacological action of plants and used for development of drugs. Many

medicinal plants have shown their antilipidemic effect and proved their efficacy in cardiovascular diseases (Nordestgard et al., 2010; Wang, 1999).

One of such plants used very often in the management of the disease by the traditional medicine practitioners of Eastern Nigeria is Desmodium velutium, a perennial plant erect or semi-erect shrub or sub-shrub up to 3m light. It is widely distributed in subtropical Asia and tropical Africa. (Amowi and Azode, 2012).

Extracts of Desmodium velutium are used traditionally in some disease conditions particularly aphrodisiac and headache. Hence,

Desomdium velutium may be a source of a pharmacological active agent useful in the treatment of aches, pains and diarrhoea. In Ghana, native doctors mix the root of Desmodium lasincarpum with some hot peppers and use it as enema to cure blood in urine. In Eastern States of Nigeria, the plant locally known as “Ikeagwuani”. (Onyegbule et al., 2012). In these present studies, I investigated the antilipidemic activity of the water (H2O) extract of

Desmodium velutinum Leaves on albino wistar rats.

Keywords: ANTILIPIDEMIC EFFECT OF WATER (H20) EXTRACT OF DESMODIUM VELUTINUM LEAVES ON ALBINO WISTAR RATS


ju


NOTE: INSTANT DOWNLOAD SERVICE

Have you made payment for this project? If YES, Get a Download Code by contacting our Customer Care.

For further enquiries, call our Hotlines: (+234) 0816-531-2322, 0811-998-2823


PROJECT TOPICS AND MATERIALS | HIRE A WRITER | HOW TO PAY FOR PROJECT

Keywords: ANTILIPIDEMIC EFFECT OF WATER (H20) EXTRACT OF DESMODIUM VELUTINUM LEAVES ON ALBINO WISTAR RATS

Got something to discuss?


 

HOW DO I MAKE PAYMENT FOR THIS PROJECT





Not the topic you are looking for ? Search here


DISCLAIMER: myproject.com.ng focus on attracting students and researchers to materials that can be used as guide, framework, and reference for their project work. All contents/materials on this website are for research purposes only and for no reason should you copy verbatim. This platform is not encouraging any form of plagiarism, neither are we advocating the use of the project materials for cheating. We strictly recommend that research project topics and materials ordered for should serve as a guide or framework only. The contents therein should be used to generate fresh ideas for your own research. Finally, myproject.com.ng will not be liable for any material used inappropriately.